Inhibition Tyrosinase Synthesis Glutathione Powder

The Core Role of Glutathione Powder is Inhibition of Tyrosinase Synthesis

1. What is glutathione powder?

glutathione powderis composed of glutamic acid, cysteine, and glycine. It contains a thiol-containing tripeptide, referred to as GSH, which is the collective name of glutathione powderglutathione powder+ thiol SH. With some whitening substances, such as tranexamic acid, are mainly used for non-whitening in the early clinical stage. Detoxification of glutathione's core role in the clinic, so it has a significant role in purifying the internal organs, such as repairing liver and kidney organs Damage, exclude heavy metals in the body. It was later discovered that glutathione powderhas the effect of whitening the skin and improving skin texture.

2. Why is glutathione powder whitening?

Core role: Inhibition of tyrosinase synthesis:

Glutathione powder can purify the internal environment, remove free radicals, and delay skin aging. So how does it achieve whitening effect?

Since the amount of melanin synthesis is positively related to tyrosinase activity, blocking tyrosinase has become the key to preventing black. There are various components that can inhibit tyrosinase activity, such as hydroquinone, kojic acid, arbutin, azelaic acid, and tranexamic acid. The mechanism of action is slightly different.

The cysteine ​​in glutathione powder has such a function. It was found in medical tests that cysteine ​​can reduce the activity of tyrosinase. Cysteine ​​is an amino acid containing thiol group. The thiol group has a strong nucleophilic effect. The thiol group can quickly react with dopaquinone to quickly form a colorless dopa derivative, thereby blocking the conversion of dopa to pigment.

So how is melanin in the skin synthesized? In fact, we are all children of the sun. When the sun shines on our body, a series of chain reactions are triggered. The tyrosine is converted into dopa under the action of tyrosinase, which is the synthesis of melanin. The first decisive step. Tyrosine is an amino acid necessary for physiological activities and is abundantly and widely found in the human body. The tyrosinase activity in darker-skinned skin is approximately three times that of lighter-skinned skin. To control skin blackening, you can find ways to block the effect of tyrosinase.

3. Glutathione-Intervenes in the synthesis of melanin, the mechanism mainly includes:

3.1 Direct inhibition of tyrosinase activity.

3.2 Free radicals can activate tyrosinase, while glutathione powder can scavenge free radicals and inhibit tyrosinase activation.

3.3 Make the melanin synthesis pathway lean to melanin (instead of melanin that darkens the skin)