Safe Non Toxic Kojic Acid Powder Medicine Raw Material CAS 501-30-4 C6H604

Safe Non Toxic Kojic Acid Powder Medicine Raw Material CAS 501-30-4 C6H604

1. The properties of kojic acidr Powder:

(1) Inhibitory ability of tyrosinase:

20ug / ml kojic acid powder can keep 70% -80% activity of tyrosinase (or polyphenol oxidase PPO) from

different sources

(2) Bacteriostatic ability:

0.2% -0.5% kojic acid powder can inhibit the growth of a variety of bacteria

(3) Antioxidant:

kojic acid powder's phenolic hydroxyl group can be reduced

(4) Chelation of metal ions:

Can chelate with Fe, Cu, Mn and other metal ions

2. kojic acid powder properties:

Can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of skin melanin

20ug / ml kojic acid powder can inhibit 70 ~ 80% of the activity of many tyrosinase (or polyphenol oxidase PPO)

Advantages: Safe and non-toxic, no sequelae of leukoplakia

Application end products: lotions, masks, lotions, skin creams, etc.

Role: Can effectively treat freckles, age spots, pigmentation, acne, etc., as a high-end whitening cosmetics.

Addition: 0.5% to 2.0% in cosmetics.

3. Stability data for kojic acid powder Powder :

kojic acid powder: Its effect was discovered when the hands of Japanese sake brewers turned white. It can effectively

inhibit tyrosine enzymes. It is soluble in water and used at concentrations between 1% and 3%. It is non-toxic and has

minimal irritation after use. It is used in the Asian food industry.

kojic acid powder easily turns yellow when exposed to light and heat, which affects the shelf life of kojic acid powder

cosmetics. Cryopreservation and the addition of ascorbic acid and sunscreen agents such as hydroxybenzophenone

(2-hydroxy-4-methoxybenzophenone) can enhance its stability.

Although kojic acid powder is soluble in water, its solubility is not large. Temperature has a great influence on its solubility,

which is conducive to concentration and cooling crystallization.

kojic acid powder is easily soluble in water, alcohol, acetone, slightly soluble in ether, ethyl acetate, chloroform, and pyridine,

and hardly soluble in most other solvents. It can be purified by crystallization in solvents such as acetone and ethyl acetate,

or it can be sublimated under reduced pressure at 150-200 ° C. The melting point reported in the literature is 151-154 ° C.

kojic acid powder and its 5,7-diethyl derivative have specific absorption peaks at 315nm and 255nm, respectively.

kojic acid powder is unstable to light and heat. The kojic acid powder solution with a concentration of 0.5% is treated at 100 ° C

for 3 hours or sunlight for 5 hours at different pH. As a result, the solution becomes pale yellow to yellow-brown in the pH range

of 5 to 7, and There was little change in pH4.

kojic acid powder interacts with ferric chloride in a special red color. This method can be used to quantify kojic acid powder.

kojic acid powder can reduce Ferrin reagent and silver ammonia nitrate. In its molecular structure, there is an alcoholic

hydroxyl group near the carbonyl group, which can form salts with various metals, and other hydroxyl groups can form

ether and ester derivatives.